In Redis Cluster architecture, when a client sends a command involving a key, it first calculates the key's slot. This slot number determines which node in the cluster owns the data for that key. The client then sends the command directly to that node. The node executes the command and returns the result to the client. For example, setting a key 'user:1' involves calculating its slot, routing the SET command to the correct node, storing the value, and confirming success. Later GET and DEL commands follow the same routing process. If the key is deleted, subsequent GET commands return nil. This process ensures efficient data distribution and retrieval across the cluster.