WSGI servers such as Gunicorn and uWSGI serve as intermediaries between the web and Flask applications. When a client sends an HTTP request, the WSGI server receives it and calls the Flask app with this request. The Flask app processes the request by running the appropriate route function and returns a response string. The WSGI server then sends this response back to the client. This process repeats for every incoming request, allowing Flask to focus on application logic while the WSGI server handles communication with the web. The execution table shows each step from server start, request receipt, Flask processing, to response delivery. Variables track the server and app states and when the response is sent. Understanding this flow helps beginners see how Flask apps run in real web environments using WSGI servers.