The @Secured annotation in Spring Boot is used to protect methods by specifying required user roles. When a method annotated with @Secured is called, Spring checks the current user's roles. If the user has the required role, the method runs normally. If not, access is denied and the method does not execute. For example, a method annotated with @Secured("ROLE_ADMIN") will only run if the user has the ROLE_ADMIN authority. The execution table shows two calls: one with a user having ROLE_USER only, which is denied, and one with ROLE_ADMIN, which is allowed. This helps secure sensitive parts of an application by role-based access control.