Deno supports TypeScript out of the box by compiling it automatically when you run a TypeScript file. You write TypeScript code with types, and Deno compiles it to JavaScript behind the scenes before running it. This means you do not need to run a separate compiler step. The type annotations are removed during compilation, so the runtime executes plain JavaScript. For example, a function with typed parameters runs normally and prints output. The execution steps include reading the code, compiling it, executing the JavaScript, and printing the result. This makes working with TypeScript easy and fast in Deno.